WEEK 11 Assignment: Off-Label Drug Use in Pediatrics
\nNumber of sources: \t3
\nPaper instructions:
\nWEEK 11. Assignment: Off-Label Drug Use in Pediatrics (see media case at the bottom of the instructions)
\nThe unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable, since very few drugs have been specifically researched and tested with children.
\nWhen treating children, prescribers often adjust dosages approved for adults to accommodate a child\u2019s weight. However, children are not just \u201csmaller\u201d adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion.<\/p>\n
Photo Credit: Getty Images
\nChildren even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.
\nTo Prepare
\nReview the interactive media piece in this week\u2019s Resources and reflect on the types of drugs used to treat pediatric patients with mood disorders.
\nReflect on situations in which children should be prescribed drugs for off-label use.
\nThink about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics.
\nBy Day 5 of Week 11
\nWrite a 1-page narrative in APA format that addresses the following:
\nExplain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples.
\nDescribe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
\nReminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The Sample Paper provided at the Walden Writing Center offers an example of those required elements (available at http:\/\/writingcenter.waldenu.edu\/57.htm). All papers submitted must use this formatting.<\/p>\n
THE MEDIA CASE TO WRITE ABOUT<\/p>\n
BACKGROUND INFORMATION
\nThe client is an 8-year-old African American male who arrives at the ER with his mother. He is exhibiting signs of depression.
\nClient complained of feeling \u201csad\u201d
\nMother reports that teacher said child is withdrawn from peers in class
\nMother notes decreased appetite and occasional periods of irritation
\nClient reached all developmental landmarks at appropriate ages
\nPhysical exam unremarkable
\nLaboratory studies WNL
\nChild referred to psychiatry for Assessment<\/p>\n
MENTAL STATUS EXAM
\nAlert & oriented X 3, speech clear, coherent, goal directed, spontaneous. Self-reported mood is \u201csad\u201d. Affect somewhat blunted, but child smiled appropriately at various points throughout the clinical interview. He denies visual or auditory hallucinations. No delusional or paranoid thought processes noted. Judgment and insight appear to be age-appropriate. He is not endorsing active suicidal ideation, but does admit that he often thinks about himself being dead and what it would be like to be dead.<\/p>\n
You administer the Children’s Depression Rating Scale, obtaining a score of 30 (indicating significant depression)<\/p>\n
RESOURCES
\n\u00a7 Poznanski, E., & Mokros, H. (1996). Child Depression Rating Scale–Revised. Los Angeles, CA: Western Psychological Services.<\/p>\n
Decision Point One
\nSelect what you should do:<\/p>\n
Begin Zoloft 25 mg orally daily
\nBegin Paxil 10 mg orally daily
\nBegin Wellbutrin 75 mg orally BID<\/p>\n
Rubric
\nExplain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples.–<\/p>\n
Excellent 36 (36%) – 40 (40%)
\nThe response accurately and thoroughly explains in detail the circumstances under which children should be prescribed drugs for off-label use.<\/p>\n
The response includes accurate and specific examples that fully support the explanation provided.
\nGood 32 (32%) – 35 (35%)
\nThe response accurately explains the circumstances under which children should be prescribed drugs for off-label use.<\/p>\n
The response includes accurate examples that support the explanation provided.
\nFair 28 (28%) – 31 (31%)
\nThe response inaccurately or vaguely explains the circumstances under which children should be prescribed drugs for off-label use.<\/p>\n
The response includes inaccurate or vague examples that may or may not support the explanation provided.
\nPoor 0 (0%) – 27 (27%)
\nThe response inaccurately and vaguely explains the circumstances under which children should be prescribed drugs for off-label use, or is missing.<\/p>\n
The response includes inaccurate and vague examples that do not support the explanation provided, or is missing.
\nExplain strategies to making off-label use and dosage of drugs safer for children from infancy to adolescence and descriptions and names of off-label drugs that require extra care and attention when used in pediatrics. Be specific.–<\/p>\n
Excellent 41 (41%) – 45 (45%)
\nThe response accurately and clearly describes in detail strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence.<\/p>\n
The response includes accurate, complete, and detailed descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
\nGood 36 (36%) – 40 (40%)
\nThe response accurately describes strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence.<\/p>\n
The response includes accurate descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
\nFair 32 (32%) – 35 (35%)
\nThe response inaccurately or vaguely describes strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence.<\/p>\n
The response includes inaccurate or vague descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.
\nPoor 0 (0%) – 31 (31%)
\nThe response inaccurately and vaguely describes strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence, or is missing.<\/p>\n
The response includes inaccurate and vague or incomplete descriptions and names of off-label drugs that require extra care and attention when used in pediatrics, or is missing.
\nWritten Expression and Formatting – Paragraph Development and Organization:
\nParagraphs make clear points that support well developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused–neither long and rambling nor short and lacking substance.–<\/p>\n
Excellent 5 (5%) – 5 (5%)
\nParagraphs and sentences follow writing standards for flow, continuity, and clarity.
\nGood 4 (4%) – 4 (4%)
\nParagraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time.
\nFair 3.5 (3.5%) – 3.5 (3.5%)
\nParagraphs and sentences follow writing standards for flow, continuity, and clarity 60%\u201379% of the time.
\nPoor 0 (0%) – 3 (3%)
\nParagraphs and sentences follow writing standards for flow, continuity, and clarity less than 60% of the time.
\nWritten Expression and Formatting – English writing standards:
\nCorrect grammar, mechanics, and proper punctuation–<\/p>\n
Excellent 5 (5%) – 5 (5%)
\nUses correct grammar, spelling, and punctuation with no errors
\nGood 4 (4%) – 4 (4%)
\nContains a few (1\u20132) grammar, spelling, and punctuation errors
\nFair 3.5 (3.5%) – 3.5 (3.5%)
\nContains several (3\u20134) grammar, spelling, and punctuation errors
\nPoor 0 (0%) – 3 (3%)
\nContains many (\u2265 5) grammar, spelling, and punctuation errors that interfere with the reader\u2019s understanding
\nWritten Expression and Formatting – The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running head, parenthetical\/in-text citations, and reference list.–<\/p>\n
Excellent 5 (5%) – 5 (5%)
\nUses correct APA format with no errors
\nGood 4 (4%) – 4 (4%)
\nContains a few (1\u20132) APA format errors
\nFair 3.5 (3.5%) – 3.5 (3.5%)
\nContains several (3\u20134) APA format errors
\nPoor 0 (0%) – 3 (3%)
\nContains many (\u2265 5) APA format errors
\nTotal Points: 100
\nName: NURS_6521_Week11_Assignment_Rubric<\/p>\n","protected":false},"excerpt":{"rendered":"
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