APA 7th. One source for each question. A paragraph for each question.
\nQUESTION 1
\nScenario 1: Acute Lymphoblastic Leukemia (ALL)
\n4 points
\nSAVE ANSWER
\nAn 11-year-old boy is brought to the clinic by his parents who states that the boy has not been eating and listless. The mother also notes that he has been easily
\nbruising without trauma as he says he is too tired to go out and play. He says his bones hurt sometimes. Mother states the child has had intermittent fevers that
\nrespond to acetaminophen.
\nMaternal history negative for pre intra, or post-partum problems
\nMH: Negative. Easily reached developmental milestones
\nPE: reveals a thin, very pale child who has bruises on his arms and legs in no particular pattern
\nLABS: CBC revealed Hemoglobin of 6.9\/dl, hematocrit of 19% and platelet count of 80 000\/mm3 The CMP demonstrated a blood urea nitrogen (BUN) of 34m
\ng\/di and creatinine of 2 9 mg\/dl.
\nDIAGNOSIS: acute leukemia and renal failure and immediately refers the patient to the Emergency Room where a pediatric hematologist has been consulted
\nand is waiting for the boy and his parents.
\nCONFIRMED DX: acute lymphoblastic leukemia (ALL) was made after extensive testing.
\nQuestion
\nExplain what ALL is?
\nScenario 1: Acute Lymphoblastic Leukemia (ALL)
\nAn 11-year-old boy is brought to the clinic by his parents who states that the boy has not been eating and listless. The mother also notes that he has been easily
\nbruising without trauma as he says he is too tired to go out and play. He says his bones hurt sometimes. Mother states the child has had intermittent fevers that
\nrespond to acetaminophen.
\nMaternal history negative for pre, intra, or post-partum problems.
\nMH: Negative. Easilv reached developmental milestones
\nPE: reveals a thin. very pale child who has bruises on his arms and legs in no particular pattern.
\nLABS: CBC revealed Hemoglobin of 6.9\/dl, hematocrit of 19%, and platelet count of 80,000\/mm? The CMP demonstrated a blood urea nitrogen (BUN) of 34m
\ng\/di and creatinine of 2.9 mg\/dl.
\nDIAGNOSIS: acute leukemia and renal failure and immediately refers the patient to the Emergency Room where a pediatric hematologist has been consulted
\nand is waiting for the boy and his parents.
\nCONEIRMED DX: acute Ivmphoblastic leukemia (ALL) was made after extensive testing
\n?
\nQuestion
\nWhy does ARF occur in some patients with ALL?
\nQUESTION 3
\n4 points
\nSAVE ANSWER
\nScenario 2: Sickle Cell Disease (SCD)
\nA 15-year-old male with known sickle cell disease (SCD) present to the ER in sickle cell crisis. The patient is crying with pain and states this is the third acute
\nepisode he has had in the last 10-months. Both parents are present and appear very anxious and teary eyed A diagnosis of acute sickle cell crisis was made
\nQuestion
\nExplain the pathophysiology of acute SCD crisis. Why is pain the predominate feature of acute crises?
\nQUESTION 4
\nScenario 2: Sickle Cell Disease (SCD)
\nA 15-vear-old male with known sickle cell disease (SCD) present to the ER in sickle cell crisis. The patient is crying with pain and states this is the third acute
\nepisode he has had in the last 10-months. Both parents are present and appear very anxious and teary eyed. A diagnosis of acute sickle cell crisis was made.
\nQuestion
\nDiscuss the genetic basis for SCD.
\nQUESTION 5
\n4 points SAVE ANSWER
\nScenario 3: Hemophilia
\n8-month infant is brought into the office due to a swollen right knee and excessive bruising. The parents have noticed bruising about a month ago but thought the
\nbruising was due to the attempts to crawl. They became concerned when the baby woke up with a swollen knee. Infant up to date on all immunizations, has not
\nhad any medical problems since birth and has met all developmental milestones.
\nH: negative for any history of bleeding disorders or other major genetic diseases
\nPE: within normal limits except for obvious bruising on the extremities and right knee. Knee is swollen but no warmth appreciated. Range of motion of knee
\nlimited due to the swelling.
\nDIAGNOSIS: hemophilia A.
\nQuestion
\nWhat is the pathophysiology of Hemophilia<\/p>\n","protected":false},"excerpt":{"rendered":"
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