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Question<\/span><\/p>\n Week 1 quiz<\/span><\/strong><\/p>\n Question 1. The major impact of the physiological changes that occur with aging is:<\/span><\/p>\n Reduced physiological reserve<\/span><\/p>\n Reduced homeostatic mechanisms<\/span><\/p>\n Impaired immunological response<\/span><\/p>\n All of the above<\/span><\/p>\n Question 2<\/span>.<\/span><\/a>\u00a0Men have faster and more efficient biotransformation of drugs and this is thought to be due to:<\/span><\/p>\n Less obesity rates than women<\/span><\/p>\n Prostate enlargement<\/span><\/p>\n Testosterone<\/span><\/p>\n Less estrogen than women<\/span><\/p>\n Question 3<\/span>.<\/span><\/a>\u00a0The cytochrome p system involves enzymes that are generally:<\/span><\/p>\n Inhibited by drugs<\/span><\/p>\n Induced by drugs<\/span><\/p>\n Inhibited or induced by drugs<\/span><\/p>\n Associated with decreased liver perfusion<\/span><\/p>\n Question 4<\/span>.<\/span><\/a>\u00a0Functional abilities are best assessed by:<\/span><\/p>\n Self-report of function<\/span><\/p>\n Observed assessment of function<\/span><\/p>\n A comprehensive head-to-toe examination<\/span><\/p>\n Family report of function<\/span><\/p>\n Question 5<\/span>.<\/span><\/a>\u00a0Iron Deficiency Anemia (IDA) is classified as a microcytic, hypochromic anemia<\/span>.<\/span><\/a>\u00a0This classification refers to which of the following laboratory data?<\/span><\/p>\n Hemoglobin and Hematocrit<\/span><\/p>\n Mean Corpuscular Volume (MCV) and Mean Corpuscular Hemoglobin (MCH)<\/span><\/p>\n Serum ferritin and serum iron<\/span><\/p>\n Total iron binding capacity and transferrin saturation<\/span><\/p>\n Question 6<\/span>.<\/span><\/a>\u00a0When interpreting laboratory data, you would expect to see the following in a patient with Anemia of Chronic Disease (ACD):<\/span><\/p>\n Hemoglobin <12 g\/dl, MCV decreased, MCH decreased<\/span><\/p>\n Hemoglobin >12 g\/dl, MCV increased, MCH increased<\/span><\/p>\n Hemoglobin <12 g\/dl, MCV normal, MCH normal<\/span><\/p>\n Hemoglobin >12 g\/dl, MCV decreased, MCH increased<\/span><\/p>\n Question 7<\/span>.<\/span><\/a>\u00a0The pathophysiological hallmark of ACD is:<\/span><\/p>\n Depleted iron stores<\/span><\/p>\n Impaired ability to use iron stores<\/span><\/p>\n Chronic unable bleeding<\/span><\/p>\n Reduced intestinal absorption of iron<\/span><\/p>\n Question 8<\/span>.<\/span><\/a>\u00a0The main focus of treatment of patients with ACD is:<\/span><\/p>\n Replenishing iron stores<\/span><\/p>\n Providing for adequate nutrition high in iron<\/span><\/p>\n Management of the underlying disorder<\/span><\/p>\n Administration of monthly vitamin B12 injections<\/span><\/p>\n Question 9<\/span>.<\/span><\/a>\u00a0In addition to the complete blood count (CBC) with differential, which of the following laboratory tests is considered to be most useful in diagnosing ACD and IDA?<\/span><\/p>\n Serum iron<\/span><\/p>\n Total iron binding capacity<\/span><\/p>\n Transferrin saturation<\/span><\/p>\n Serum ferritin<\/span><\/p>\n Question 10<\/span>.<\/span><\/a>\u00a0Symptoms in the initial human immunodeficiency virus (HIV) infection include all of the following except:<\/span><\/p>\n Sore throat<\/span><\/p>\n Fever<\/span><\/p>\n Weight loss<\/span><\/p>\n Headache<\/span><\/p>\n Question 11<\/span>.<\/span><\/a>\u00a0Essential parts of a health history include all of the following except:<\/span><\/p>\n Chief complaint<\/span><\/p>\n History of the present illness<\/span><\/p>\n Current vital signs<\/span><\/p>\n All of the above are essential history components<\/span><\/p>\n Question 12<\/span>.<\/span><\/a>Which of the following clinical reasoning tools is defined as evidence-based resource based on mathematical modeling to express the likelihood of a condition in select situations, settings, and\/or patients?<\/span><\/p>\n Clinical practice guideline<\/span><\/p>\n Clinical decision rule<\/span><\/p>\n Clinical algorithm<\/span><\/p>\n Clinical recommendation<\/span><\/p>\n Question 13<\/span>.<\/span><\/a>\u00a0The first step in the genomic assessment of a patient is obtaining information regarding:<\/span><\/p>\n Family history<\/span><\/p>\n Environmental exposures<\/span><\/p>\n Lifestyle and behaviors<\/span><\/p>\n Current medications<\/span><\/p>\n Question 14<\/span>.<\/span><\/a>In autosomal recessive (AR) disorders, individuals need:<\/span><\/p>\n Only one mutated gene on the sex chromosomes to acquire the disease<\/span><\/p>\n Only one mutated gene to acquire the disease<\/span><\/p>\n Two mutated genes to acquire the disease<\/span><\/p>\n Two mutated genes to become carriers<\/span><\/p>\n Question 15<\/span>.<\/span><\/a>\u00a0In AR disorders, carriers have:<\/span><\/p>\n Two mutated genes; two from one parent that cause disease<\/span><\/p>\n A mutation on a sex chromosome that causes a disease<\/span><\/p>\n A single gene mutation that causes the disease<\/span><\/p>\n One copy of a gene mutation but not the disease<\/span><\/p>\n Question 16<\/span>.<\/span><\/a>\u00a0A woman with an X-linked dominant disorder will:<\/span><\/p>\n Not be affected by the disorder herself<\/span><\/p>\n Transmit the disorder to 50% of her offspring (male or female)<\/span><\/p>\n Not transmit the disorder to her daughters<\/span><\/p>\n Transmit the disorder to only her daughters<\/span><\/p>\n Question 17<\/span>.<\/span><\/a>\u00a0According to the Genetic Information Nondiscrimination Act (GINA):<\/span><\/p>\n Nurse Practitioners (NPs) should keep all genetic information of patients confidential<\/span><\/p>\n NPs must obtain informed consent prior to genetic testing of all patients<\/span><\/p>\n Employers cannot inquire about an employee\u2019s genetic information<\/span><\/p>\n All of the above<\/span><\/p>\n Question 18<\/span>.<\/span><\/a>\u00a0Which of the following would be considered a \u201cred flag\u201d that requires more investigation in a patient assessment?<\/span><\/p>\n Colon cancer in family member at age 70<\/span><\/p>\n Breast cancer in family member at age 75<\/span><\/p>\n Myocardial infarction in family member at age 35<\/span><\/p>\n All of the above<\/span><\/p>\n Question 19<\/span>.<\/span><\/a>\u00a0Your 2-year-old patient shows facial features, such as epicanthal folds, up-slanted palpebral fissures, single transverse palmar crease, and a low nasal bridge<\/span>.<\/span><\/a>\u00a0These are referred to as:<\/span><\/p>\n Variable expressivity related to inherited disease<\/span><\/p>\n Dysmorphic features related to genetic disease<\/span><\/p>\n De novo mutations of genetic disease<\/span><\/p>\n