NR 508 Final Exam Answers \u2013 Chamberlain College Of Nursing
\nNR 508 Final Exam Answers \u2013 Chamberlain College Of Nursing<\/p>\n
Pattern Questions:<\/p>\n
A number of Alternative<\/p>\n
Establish the selection that greatest completes the assertion or solutions the Question Assignment.<\/p>\n
____ 1. Nurse practitioner prescriptive authority is regulated by:<\/p>\n
1.\tThe Nationwide Council of State Boards of Nursing
\n2.\tThe U.S. Drug Enforcement Administration
\nthree.\tThe State Board of Nursing for every state
\nfour.\tThe State Board of Pharmacy<\/p>\n
____ 2. The advantages to the affected person of getting an Superior Apply Registered Nurse (APRN) prescriber embody:<\/p>\n
1.\tNurses know extra about Pharmacology than different prescribers as a result of they take it each of their fundamental nursing program and of their APRN program.
\n2.\tNurses look after the affected person from a holistic method and embody the affected person in determination making concerning their care.
\nthree.\tAPRNs are much less more likely to prescribe narcotics and different managed substances.
\nfour.\tAPRNs are in a position to prescribe independently in all states, whereas a doctor\u2019s Helpant must have a doctor supervising their follow.<\/p>\n
____ three. Medical judgment in prescribing consists of:<\/p>\n
1.\tFactoring in the associated fee to the affected person of the medicine prescribed
\n2.\tAt all times prescribing the most recent medicine obtainable for the illness course of
\nthree.\tHanding out drug samples to poor sufferers
\nfour.\tPrescribing all generic medicines to chop prices<\/p>\n
____ four. Standards for selecting an efficient drug for a dysfunction embody:<\/p>\n
1.\tAsking the affected person what drug they suppose would work greatest for them
\n2.\tConsulting nationally acknowledged pointers for illness administration
\nthree.\tPrescribing medicines which are obtainable as samples earlier than writing a prescription
\nfour.\tFollowing U.S. Drug Enforcement Administration pointers for prescribing<\/p>\n
____ 5. Nurse practitioner follow might thrive beneath health-care reform due to:<\/p>\n
1.\tThe demonstrated capability of nurse practitioners to regulate prices and enhance affected person outcomes
\n2.\tThe truth that nurse practitioners will be capable of follow independently
\nthree.\tThe truth that nurse practitioners can have full reimbursement beneath health-care reform
\nfour.\tThe power to shift accountability for Medicaid to the state degree<\/p>\n
A number of Alternative<\/p>\n
Establish the selection that greatest completes the assertion or solutions the Question Assignment.<\/p>\n
____ 1. A affected person\u2019s dietary consumption and laboratory outcomes mirror hypoalbuminemia. That is essential to prescribing as a result of:<\/p>\n
1.\tDistribution of medicine to focus on tissue could also be affected.
\n2.\tThe solubility of the drug is not going to match the location of absorption.
\nthree.\tThere can be much less free drug obtainable to generate an impact.
\nfour.\tMedication sure to albumin are readily excreted by the kidneys.<\/p>\n
____ 2. Medication which have a major first-pass impact:<\/p>\n
1.\tHave to be given by the enteral (oral) route solely
\n2.\tBypass the hepatic circulation
\nthree.\tAre quickly metabolized by the liver and should have little if any desired motion
\nfour.\tAre transformed by the liver to extra lively and fat-soluble kinds<\/p>\n
____ three. The route of excretion of a unstable drug will seemingly be the:<\/p>\n
1.\tKidneys
\n2.\tLungs
\nthree.\tBile and feces
\nfour.\tPores and skin<\/p>\n
____ four. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir of the drug. Storage reservoirs:<\/p>\n
1.\tGuarantee that the drug will attain its supposed goal tissue
\n2.\tAre the rationale for giving loading doses
\nthree.\tImprove the size of time a drug is on the market and lively
\nfour.\tAre commonest in collagen tissues<\/p>\n
____ 5. The NP chooses to present cephalexin each eight hours primarily based on data of the drug\u2019s:<\/p>\n
1.\tPropensity to go to the goal receptor
\n2.\tOrganic half-life
\nthree.\tPharmacodynamics
\nfour.\tSecurity and unwanted side effects<\/p>\n
____ 6. Azithromycin dosing requires that the primary day\u2019s dosage be twice these of the opposite four days of the prescription. That is thought-about a loading dose. A loading dose:<\/p>\n
1.\tQuickly achieves drug ranges within the therapeutic vary
\n2.\tRequires four- to five-half-lives to achieve
\nthree.\tIs influenced by renal operate
\nfour.\tIs immediately associated to the drug circulating to the goal tissues<\/p>\n
____ 7. The time limit on the drug focus curve that signifies the primary signal of a therapeutic impact is the:<\/p>\n
1.\tMinimal adversarial impact degree
\n2.\tPeak of motion
\nthree.\tOnset of motion
\nfour.\tTherapeutic vary<\/p>\n
____ eight. Phenytoin requires that a trough degree be drawn. Peak and trough ranges are finished:<\/p>\n
1.\tWhen the drug has a large therapeutic vary
\n2.\tWhen the drug can be administered for a short while solely
\nthree.\tWhen there’s a excessive correlation between the dose and saturation of receptor websites
\nfour.\tTo find out if a drug is within the therapeutic vary<\/p>\n
____ 9. A laboratory end result signifies that the height degree for a drug is above the minimal poisonous focus. Which means the:<\/p>\n
1.\tFocus will produce therapeutic results
\n2.\tFocus will produce an adversarial response
\nthree.\tTime between doses should be shortened
\nfour.\tPeriod of motion of the drug is simply too lengthy<\/p>\n
____ 10. Medication which are receptor agonists might show what property?<\/p>\n
1.\tIrreversible binding to the drug receptor website
\n2.\tUpregulation with persistent use
\nthree.\tDesensitization or downregulation with steady use
\nfour.\tInverse relationship between drug focus and drug motion<\/p>\n
____ 11. Medication which are receptor antagonists, similar to beta blockers, might trigger:<\/p>\n
1.\tDownregulation of the drug receptor
\n2.\tAn exaggerated response if abruptly discontinued
\nthree.\tPartial blockade of the results of agonist medicine
\nfour.\tAn exaggerated response to aggressive drug agonists<\/p>\n
____ 12. Elements that have an effect on gastric drug absorption embody:<\/p>\n
1.\tLiver enzyme exercise
\n2.\tProtein-binding properties of the drug molecule
\nthree.\tLipid solubility of the drug
\nfour.\tCapacity to chew and swallow<\/p>\n
____ 13. Medication administered by way of IV:<\/p>\n
1.\tMust be lipid soluble so as to be simply absorbed
\n2.\tStart distribution into the physique instantly
\nthree.\tAre simply absorbed if they’re nonionized
\nfour.\tMight use pinocytosis to be absorbed<\/p>\n
____ 14. When a medicine is added to a routine for a synergistic impact, the mixed impact of the medicine is:<\/p>\n
1.\tThe sum of the results of every drug individually
\n2.\tHigher than the sum of the results of every drug individually
\nthree.\tLower than the impact of every drug individually
\nfour.\tNot predictable, because it varies with every particular person<\/p>\n
____ 15. Which of the next statements about bioavailability is true?<\/p>\n
1.\tBioavailability points are particularly vital for medicine with slender therapeutic ranges or sustained-release mechanisms.
\n2.\tAll manufacturers of a drug have the identical bioavailability.
\nthree.\tMedication which are administered greater than as soon as a day have higher bioavailability than medicine given as soon as day by day.
\nfour.\tCombining an lively drug with an inert substance doesn’t have an effect on bioavailability.<\/p>\n
____ 16. Which of the next statements in regards to the main distribution obstacles (blood-brain or fetal-placental) is true?<\/p>\n
1.\tWater soluble and ionized medicine cross these obstacles quickly.
\n2.\tThe blood-brain barrier slows the entry of many medicine into and from mind cells.
\nthree.\tThe fetal-placental barrier protects the fetus from medicine taken by the mom.
\nfour.\tLipid-soluble medicine don’t go these obstacles and are secure for pregnant girls.<\/p>\n
____ 17. Medication are metabolized primarily by the liver by way of part I or part II reactions. The aim of each of some of these reactions is to:<\/p>\n
1.\tInactivate prodrugs earlier than they are often activated by goal tissues
\n2.\tChange the medicine to allow them to cross plasma membranes
\nthree.\tChange drug molecules to a kind that an excretory organ can excrete
\nfour.\tMake these medicine extra ionized and polar to facilitate excretion<\/p>\n
____ 18. As soon as they’ve been metabolized by the liver, the metabolites could also be:<\/p>\n
1.\tExtra lively than the guardian drug
\n2.\tMuch less lively than the guardian drug
\nthree.\tCompletely \u201cdeactivated\u201d so they’re excreted with none impact
\nfour.\tThe entire above<\/p>\n
____ 19. All medicine proceed to behave within the physique till they’re modified or excreted. The power of the physique to excrete medicine by way of the renal system could be elevated by:<\/p>\n
1.\tDiminished circulation and perfusion of the kidney
\n2.\tContinual renal illness
\nthree.\tCompetitors for a transport website by one other drug
\nfour.\tUnbinding a nonvolatile drug from plasma proteins<\/p>\n
____ 20. Regular state is:<\/p>\n
1.\tThe purpose on the drug focus curve when absorption exceeds excretion
\n2.\tWhen the quantity of drug within the physique stays fixed
\nthree.\tWhen the quantity of drug within the physique stays beneath the minimal poisonous focus
\nfour.\tThe entire above<\/p>\n
____ 21. Two completely different ache medicines are given collectively for ache aid. The drug\u2014drug interplay is:<\/p>\n
1.\tSynergistic
\n2.\tAntagonistic
\nthree.\tPotentiative
\nfour.\tAdditive<\/p>\n
____ 22. Actions taken to cut back drug\u2014drug interplay issues embody the entire following EXCEPT:<\/p>\n
1.\tDecreasing the dosage of one of many medicine
\n2.\tScheduling their administration at completely different occasions
\nthree.\tPrescribing a 3rd drug to counteract the adversarial response of the mixture
\nfour.\tDecreasing the dosage of each medicine<\/p>\n
____ 23. Section I oxidative-reductive processes of drug metabolism require sure dietary parts. Which of the next would cut back or inhibit this course of?<\/p>\n
1.\tProtein malnutrition
\n2.\tIron-deficiency anemia
\nthree.\tEach 1 and a pair of
\nfour.\tNeither 1 nor 2<\/p>\n
____ 24. The time required for the quantity of drug within the physique to lower by 50% known as:<\/p>\n
1.\tRegular state
\n2.\tHalf-life
\nthree.\tSection II metabolism
\nfour.\tDiminished bioavailability time<\/p>\n
____ 25. An agonist prompts a receptor and stimulates a response. When given regularly over time, the physique might:<\/p>\n
1.\tUpregulate the entire variety of receptors
\n2.\tBlock the receptor with a partial agonist
\nthree.\tAlter the drug\u2019s metabolism
\nfour.\tDownregulate the numbers of that particular receptor<\/p>\n
____ 26. Drug antagonism is greatest outlined as an impact of a drug that:<\/p>\n
1.\tResults in main physiological and psychological dependence
\n2.\tIs modified by the concurrent administration of one other drug
\nthree.\tCan’t be metabolized earlier than one other dose is run
\nfour.\tResults in a decreased physiological response when mixed with one other drug<\/p>\n
____ 27. Directions to a consumer concerning self-administration of oral enteric-coated tablets ought to embody which of the next statements?<\/p>\n
1.\t\u201cKeep away from some other oral medicines whereas taking this drug.\u201d
\n2.\t\u201cIf swallowing this pill is tough, dissolve it in three ounces of orange juice.\u201d
\nthree.\t\u201cThe pill could also be crushed in case you have any problem taking it.\u201d
\nfour.\t\u201cTo attain greatest impact, take the pill with a minimum of eight ounces of fluid.\u201d<\/p>\n
____ 28. The foremost motive for not crushing a sustained-release capsule is that, if crushed, the coated beads of the medicine may probably end in:<\/p>\n
1.\tDisintegration
\n2.\tToxicity
\nthree.\tMalabsorption
\nfour.\tDeterioration<\/p>\n
____ 29. Which of the next substances is the probably to be absorbed within the intestines moderately than within the abdomen?<\/p>\n
1.\tSodium bicarbonate
\n2.\tAscorbic acid
\nthree.\tSalicylic acid
\nfour.\tGlucose<\/p>\n
____ 30. Which of the next variables is a think about drug absorption?<\/p>\n
1.\tThe smaller the floor space for absorption, the extra quickly the drug is absorbed.
\n2.\tA wealthy blood provide to the realm of absorption results in higher absorption.
\nthree.\tThe much less soluble the drug, the extra simply it’s absorbed.
\nfour.\tIonized medicine are simply absorbed throughout the cell membrane.<\/p>\n
____ 31. A bonus of prescribing a sublingual medicine is that the medicine is:<\/p>\n
1.\tAbsorbed quickly
\n2.\tExcreted quickly
\nthree.\tMetabolized minimally
\nfour.\tDistributed equally<\/p>\n
____ 32. Medication that use CYP 3A4 isoenzymes for metabolism might:<\/p>\n
1.\tInduce the metabolism of one other drug
\n2.\tInhibit the metabolism of one other drug
\nthree.\tEach 1 and a pair of
\nfour.\tNeither 1 nor 2<\/p>\n
____ 33. Therapeutic drug ranges are drawn when a drug reaches regular state. Medication attain regular state:<\/p>\n
1.\tAfter the second dose
\n2.\tAfter 4 to 5 half-lives
\nthree.\tWhen the affected person feels the total impact of the drug
\nfour.\tOne hour after IV administration<\/p>\n
____ 34. Upregulation or hypersensitization might result in:<\/p>\n
1.\tElevated response to a drug
\n2.\tDecreased response to a drug
\nthree.\tAn exaggerated response if the drug is withdrawn
\nfour.\tRefractoriness or full lack of response<\/p>\n","protected":false},"excerpt":{"rendered":"
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