Problem Set 1: Amino Acids and Peptide Synthesis (15 pts)\tName:_________________________
\nMultiple Choice: Place your answer in the box provided. (0.5 pt each)
\n1.\tWhich of the following amino acids is NOT classified as non-polar?
\na.\ttryptophan
\nb.\tmethionine
\nc.\tvaline
\nd.\tserine<\/p>\n
2.\tWhich of the following statements is true regarding peptides?
\na.\tPeptide sequences are written from C-terminus to N-terminus.
\nb.\tPeptides are synthesized in the body from C-terminus to N-terminus.
\nc.\tThe amides in the peptide backbone prefer the cis conformation.
\nd.\tThe amides in the peptide backbone are planar.<\/p>\n
3.\tWhich of the following amino acid protecting groups is NOT removed with strong acid?
\na.\tBoc
\nb.\tt-butyl
\nc.\ttrityl
\nd.\talloc<\/p>\n
4.\tWhich reason below best describes why an orthogonal protecting group strategy is used during peptide synthesis?
\na.\tTo prevent amino acid side chain reactivity while allowing synthesis to continue on the N-terminus.
\nb.\tTo limit the amount of epimerization that occurs.
\nc.\tTo activate the C-terminal carboxylic acid for amide bond formation.
\nd.\tTo confirm that a reaction worked through the observation of a purple color.<\/p>\n
5.\tProvide the complete structure for each of the amino acids below. (6 pts)
\na.\tFmoc-Tyr(Trt)-OH<\/p>\n
b.\tH-Lys(Cbz)-OtBu<\/p>\n
c.\tBoc-Asp(Alloc)-OH<\/p>\n
6.\tWrite the complete short-hand notation for the amino acids below. (3 pts)
\na.<\/p>\n
___________________________________________<\/p>\n
b.<\/p>\n
___________________________________________<\/p>\n
7.\tWrite the sequence for the peptide below using three letter codes. (2 pts)<\/p>\n
8.\tWrite the sequence for the peptide below using single letter codes. (2 pts)<\/p>\n
—<\/p>\n
Set 1 of Problems: Amino Acids and Peptide Synthesis (15 pts) Name:_________________________
\nFill in the blanks with your answer to the multiple-choice question. (each worth 0.5 point)<\/p>\n
1. Which of the following amino acids is NOT a non-polar amino acid?<\/p>\n
a. tryptophan<\/p>\n
b. methionine
\nq
\nc. valine<\/p>\n
d. serine<\/p>\n
2. Which of the following claims about peptides is correct?<\/p>\n
a. Peptide sequences are written in the order C-terminus-N-terminus.<\/p>\n
b. In the body, peptides are produced from the C-terminus to the N-terminus.<\/p>\n
c. Peptide backbone amides favor the cis conformation.<\/p>\n
d. The planar amides in the peptide backbone.<\/p>\n
3. Which of the following amino acid protecting groups does not dissolve in strong acid?<\/p>\n
a. Boc<\/p>\n
b. t-butyl<\/p>\n
c. trityl<\/p>\n
d. alloc<\/p>\n
4. Which of the following reasons best depicts why an orthogonal<\/p>\n","protected":false},"excerpt":{"rendered":"
Problem Set 1: Amino Acids and Peptide Synthesis (15 pts) Name:_________________________ Multiple Choice: Place your answer in the box provided. (0.5 pt each) 1. Which\u2026<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7650,7624,1387,7654,667,7649,7652],"tags":[613,7594,1394,7598,7595,7593,7597,7599,7601,7590,7596,7591,7592],"class_list":["post-92750","post","type-post","status-publish","format-standard","hentry","category-assignment-writing-help","category-dissertation-help","category-dissertation-writing-service","category-healthcare-assignment-help","category-nursing-essay","category-research-essay-help","category-write-my-essay-online","tag-best-dissertation-writing-services-uk","tag-cheap-custom-essay-writing-services","tag-custom-research-paper-writers","tag-custom-research-papers-writing-service","tag-essay-writer-websites","tag-essay-writing-service-quality-cheap","tag-free-research-paper-writing-service","tag-help-me-write-a-research-paper","tag-i-need-help-with-my-dissertation","tag-professional-dissertation-writing-service","tag-quick-essay-writing-service","tag-top-rated-dissertation-writing-services","tag-top-uk-dissertation-writing-services"],"_links":{"self":[{"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/posts\/92750","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/comments?post=92750"}],"version-history":[{"count":0,"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/posts\/92750\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/media?parent=92750"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/categories?post=92750"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.studyproessays.com\/help\/wp-json\/wp\/v2\/tags?post=92750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}