NURS 6501N-38: Advanced Pathophysiology<\/p>\n
Week 1: Basic Concepts of Physiology and Factors That Influence Disease
\nImagine the pain, suffering, and frustration patients feel when they find out they have been misdiagnosed with a disease or disorder. Additionally, consider the financial implications and consequences for time-sensitive disorders such as cancer. Since most disorders have multiple symptoms, and these symptoms are often prevalent in more than one disorder, it can be difficult for health care providers to diagnose patients correctly.<\/p>\n
As an advanced practice nurse making decisions related to diagnosis and treatment, you need to have an in-depth understanding of the pathophysiology of disorders, as well as factors that influence them. This week, in preparation for your role in evaluating patients, you examine the impact of patient factors on disease. You also explore the pathophysiology of disorders and resulting alterations in cellular function.<\/p>\n
Learning Objectives<\/p>\n
Students will:<\/p>\n
\u2022 Evaluate the impact of patient factors on disease
\n\u2022 Analyze the pathophysiology of alterations in cellular function
\n\u2022 Understand and apply key terms, concepts, and principles related to physiology and factors that influence disease
\nRequired Readings<\/p>\n
Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.<\/p>\n
\u2022 Chapter 1, \u201cCellular Biology\u201d
\nThis chapter reviews cellular biology to establish a foundation for exploring the pathophysiology of disease. It also covers the structure and function of cellular components, cell-to-cell adhesions, cellular communication, cellular metabolism, membrane transport, the cell cycle, and tissues.<\/p>\n
\u2022 Chapter 2, \u201cGenes and Genetic Diseases\u201d
\nThis chapter explores genetic disorders and factors that impact genetic disorders. It also examines how mutations and chromosomal abnormalities lead to transmission of genetic disorders.<\/p>\n
\u2022 Chapter 4, \u201cAltered Cellular and Tissue Biology\u201d
\nThis chapter examines disorders related to cell adaptation, injury, and death. It also explores disorders associated with altered cellular and tissue function as a result of aging.<\/p>\n
Hammer, G. G. , & McPhee, S. (2014). Pathophysiology of disease: An introduction to clinical medicine. (7th ed.) New York, NY: McGraw-Hill Education.<\/p>\n
\u2022 Chapter 2, \u201cGenetic Disease\u201d
\nThis chapter reviews the clinical manifestations, pathophysiology, and genetic principles of genetic diseases. It also explores different types of genetic diseases and the mechanisms involved.<\/p>\n
\u2022 Chapter 5, \u201cNeoplasia\u201d
\nThis chapter explores various disorders associated with neoplasia. It also covers causes and effects of common cancers and tumors resulting from neoplasia. NURS 6501 Course Discussions & Assignment Essays<\/p>\n
Required Media<\/p>\n
Laureate Education, Inc. (Executive Producer). (2012d). Introduction to advanced pathophysiology. Baltimore, MD: Author.<\/p>\n
Note: The approximate length of this media piece is 10 minutes.<\/p>\n
In this media presentation, Dr. Terry Buttaro, associate professor of practice at Simmons School of Nursing and Health Sciences, discusses the importance of pathophysiology for the advanced practice nurse.<\/p>\n
Discussion: Factors That Influence Disease<\/p>\n
In clinical settings, some of the most common questions that patients ask are Why do I have this? What caused this disorder? Will it ever go away? These emotional questions can be difficult to ask and to answer. However, for patients to come to terms with their diagnoses and adhere to treatment plans, they must have an understanding of factors that might have caused, or continue to impact, their disorders. As an advanced practice nurse, it is important that you are able to explain disorders, associated alterations and symptoms, and changes that might occur within your patients\u2019 bodies.<\/p>\n
To Prepare<\/p>\n
\u2022 Review this week\u2019s media presentation with Dr. Terry Buttaro. Reflect on the importance of developing an in-depth understanding of pathophysiology.
\n\u2022 Select a disorder from the following list:
\no Adrenal insufficiency (Addison\u2019s disease)
\no Atherosclerosis
\no Cholelithiasis (gallstones)
\no Colon cancer
\no Cystic fibrosis
\no Hemophilia
\no Nephrolithiasis (kidney stones)
\no Osteoporosis
\no Parkinson\u2019s disease
\no Tuberculosis
\n\u2022 Select one of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how that factor might impact your selected disorder, as well as potential associated alterations and symptoms.
\n\u2022 Identify the pathophysiology of the associated alterations, including the normal and altered cellular function. Consider both intra- and extra-cellular changes that occur.
\nBy Day 3<\/p>\n
Post a brief description of a patient scenario involving the disorder and the factor you selected. Explain how the factor might impact your selected disorder, as well as potential associated alterations and symptoms. Finally, explain the pathophysiology of the associated alterations, including changes in cellular function.<\/p>\n
Read a selection of your colleagues\u2019 responses.<\/p>\n
By Day 6<\/p>\n
Respond to at least two of your colleagues on two different days who selected different disorders and factors than you, in the following ways:<\/p>\n
\u2022 Share insights on how the factor you selected impacts the pathophysiology of the disorder your colleague selected.
\n\u2022 Expand on your colleague\u2019s posting by providing additional insights or contrasting perspectives based on readings and evidence. NURS 6501 Course Discussions & Assignment Essays<\/p>\n","protected":false},"excerpt":{"rendered":"
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