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Innate Immunity: Inflammation and Wound Healing Chp 6
A 7-year-old boy is playing outside when he sees a snake and tries to pick it up. What he thinks is a nonvenomous snake is actually a member of the venomous pit viper species, a copperhead. The snake curls and bites the young boy on the palm of his right hand just below his thumb. He cries out in pain, drops the snake, and runs to his parents. The parents immediately drive the child to a local hospital’s emergency department. Upon examination, the child’s right hand is swollen and red from the fingertips to his elbow. The emergency department physician orders that the child begin antivenin therapy.
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1. Which of the following is most important in preventing further damage to surrounding tissues?
A. Mast cells
B. Neutrophils
C. Platelets
D. Anaphylatoxins
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2. After several days of treatment and observation, the child is allowed to return home. He is able to wiggle all of his fingers, has full sensation, and can flex and extend his wrist without pain. The bite area remains red and scabbed over. As he continues to recover, his body must continue the reconstruction phase and then move on to the maturation phase. The most important cells during the reconstructive phase of wound healing are:
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A. Fibroblasts
B. Epithelial cells
C. Keloids
D. Prostaglandins
Briefly explain the pathophysiology of how our immune system reacts to a poisonous bite.
